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Potassium

Its Uses:

Potassium is measured as part of a routine medical exam, when you have symptoms such as weakness and/or cardiac arrhythmia, or when an electrolyte imbalance is suspected; at regular intervals when you are taking a medication and/or have a disease or condition, such as high blood pressure (hypertension) or kidney disease, that can affect your potassium level.

Interfering Factors:

  • • Opening and closing of the hand with a tourniquet in place may increase potassium levels.
  • • Hemolysis of the blood during venipuncture or during laboratory processing causes increased levels.
  • • Drugs that may cause increased potassium levels include: aminocaproic acid, antibiotics, antineoplastic drugs, captopril, heparin, histamine, isoniazid, lithium, mannitol, potassium-sparing diuretics, potassium supplements and succinylcholine.
  • • Drugs that may cause decreased levels of potassium include: aminosalicylic acid, glucose infusions, amphotericin B, carbenicillin, cisplatin, diuetics, insuin, laxatives, lithium carbonate, salicylates (aspirin), and sodium polystrene sulfonate.

Diagnostic Significance:

Increased Levels of Potassium (hyperkalemia) may indicate:

  • •    Excessive dietary intake
  • •    Excessive IV intake
  • •    Acute or chonic renal failure
  • •    Addisons disease
  • •    Hypoaldosteronism
  • •    Crush injury to tissues
  • •    Hemolysis
  • •    Infection
  • •    Acidosis
  • •    Dehydration

Decreased level of potassium (hypokalemia) may indicate:

  • •    Deficient dietary intake
  • •    Deficient IV intake
  • •    Burns
  • •    Gastrointestinal disorders
  • •    Hyperaldosteronism
  • •    Cushing syndrome
  • •    Licorice ingestion
  • •    Infection
  • •    Renal tubularacidosis
    •    Insulin administration
  • •    Ascites
  • •    Renal artery stenosis
  • •    Cystic fibrosis

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